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h gr 113808  (Revvity)


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  • 90

    Structured Review

    Revvity h gr 113808
    H Gr 113808, supplied by Revvity, used in various techniques. Bioz Stars score: 90/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/h+gr+113808/GR113808%2C%5BN-methyl-3H%5D/pm24128816-336-21-23
    Average 90 stars, based on 12 article reviews
    h gr 113808 - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Binding Assay:

    Article Title: Synthesis and Structure-Affinity Relationships of Selective High-Affinity 5-HT 4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers
    Article Snippet: .. For radioligand binding studies, 600 μg of membrane were incubated in duplicate at 37 °C for 30 min with [ 3 H]GR 113808 (Perkin Elmer), fixed concentration of compound and HEPES buffer 50 mM pH 7.4 at 37 °C. .. Incubation was terminated by rapid vacuum filtration through 0.5% polyethylenimine-presoaked Whatman GF/B filters (Alpha Biotech) using a Brandel Cell Harvester.

    Article Title: Design of fluorinated 5-HT4R antagonists: Influence of the basicity and lipophilicity toward the 5-HT4R binding affinities
    Article Snippet: Accepted Manuscript Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipo‐ philicity toward the 5-HT4R binding affinities Clement Q. Fontenelle, Zhong Wang, Christine Fossey, Thomas Cailly, Bruno Linclau, Frederic Fabis PII: S0968-0896(13)00764-5 DOI: http://dx.doi.org/10.1016/j.bmc.2013.08.061 Reference: BMC 11077 To appear in: Bioorganic & Medicinal Chemistry Received Date: 25 July 2013 Revised Date: 27 August 2013 Accepted Date: 28 August 2013 Please cite this article as: Fontenelle, C.Q., Wang, Z., Fossey, C., Cailly, T., Linclau, B., Fabis, F., Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipophilicity toward the 5-HT4R binding affinities, Bioorganic & Medicinal Chemistry (2013), doi: http://dx.doi.org/10.1016/j.bmc.2013.08.061 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form.

    Membrane:

    Article Title: Synthesis and Structure-Affinity Relationships of Selective High-Affinity 5-HT 4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers
    Article Snippet: .. For radioligand binding studies, 600 μg of membrane were incubated in duplicate at 37 °C for 30 min with [ 3 H]GR 113808 (Perkin Elmer), fixed concentration of compound and HEPES buffer 50 mM pH 7.4 at 37 °C. .. Incubation was terminated by rapid vacuum filtration through 0.5% polyethylenimine-presoaked Whatman GF/B filters (Alpha Biotech) using a Brandel Cell Harvester.

    Article Title: Design of fluorinated 5-HT4R antagonists: Influence of the basicity and lipophilicity toward the 5-HT4R binding affinities
    Article Snippet: Accepted Manuscript Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipo‐ philicity toward the 5-HT4R binding affinities Clement Q. Fontenelle, Zhong Wang, Christine Fossey, Thomas Cailly, Bruno Linclau, Frederic Fabis PII: S0968-0896(13)00764-5 DOI: http://dx.doi.org/10.1016/j.bmc.2013.08.061 Reference: BMC 11077 To appear in: Bioorganic & Medicinal Chemistry Received Date: 25 July 2013 Revised Date: 27 August 2013 Accepted Date: 28 August 2013 Please cite this article as: Fontenelle, C.Q., Wang, Z., Fossey, C., Cailly, T., Linclau, B., Fabis, F., Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipophilicity toward the 5-HT4R binding affinities, Bioorganic & Medicinal Chemistry (2013), doi: http://dx.doi.org/10.1016/j.bmc.2013.08.061 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form.

    Incubation:

    Article Title: Synthesis and Structure-Affinity Relationships of Selective High-Affinity 5-HT 4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers
    Article Snippet: .. For radioligand binding studies, 600 μg of membrane were incubated in duplicate at 37 °C for 30 min with [ 3 H]GR 113808 (Perkin Elmer), fixed concentration of compound and HEPES buffer 50 mM pH 7.4 at 37 °C. .. Incubation was terminated by rapid vacuum filtration through 0.5% polyethylenimine-presoaked Whatman GF/B filters (Alpha Biotech) using a Brandel Cell Harvester.

    Article Title: Design of fluorinated 5-HT4R antagonists: Influence of the basicity and lipophilicity toward the 5-HT4R binding affinities
    Article Snippet: Accepted Manuscript Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipo‐ philicity toward the 5-HT4R binding affinities Clement Q. Fontenelle, Zhong Wang, Christine Fossey, Thomas Cailly, Bruno Linclau, Frederic Fabis PII: S0968-0896(13)00764-5 DOI: http://dx.doi.org/10.1016/j.bmc.2013.08.061 Reference: BMC 11077 To appear in: Bioorganic & Medicinal Chemistry Received Date: 25 July 2013 Revised Date: 27 August 2013 Accepted Date: 28 August 2013 Please cite this article as: Fontenelle, C.Q., Wang, Z., Fossey, C., Cailly, T., Linclau, B., Fabis, F., Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipophilicity toward the 5-HT4R binding affinities, Bioorganic & Medicinal Chemistry (2013), doi: http://dx.doi.org/10.1016/j.bmc.2013.08.061 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form.

    Concentration Assay:

    Article Title: Synthesis and Structure-Affinity Relationships of Selective High-Affinity 5-HT 4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers
    Article Snippet: .. For radioligand binding studies, 600 μg of membrane were incubated in duplicate at 37 °C for 30 min with [ 3 H]GR 113808 (Perkin Elmer), fixed concentration of compound and HEPES buffer 50 mM pH 7.4 at 37 °C. .. Incubation was terminated by rapid vacuum filtration through 0.5% polyethylenimine-presoaked Whatman GF/B filters (Alpha Biotech) using a Brandel Cell Harvester.

    Article Title: Design of fluorinated 5-HT4R antagonists: Influence of the basicity and lipophilicity toward the 5-HT4R binding affinities
    Article Snippet: Accepted Manuscript Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipo‐ philicity toward the 5-HT4R binding affinities Clement Q. Fontenelle, Zhong Wang, Christine Fossey, Thomas Cailly, Bruno Linclau, Frederic Fabis PII: S0968-0896(13)00764-5 DOI: http://dx.doi.org/10.1016/j.bmc.2013.08.061 Reference: BMC 11077 To appear in: Bioorganic & Medicinal Chemistry Received Date: 25 July 2013 Revised Date: 27 August 2013 Accepted Date: 28 August 2013 Please cite this article as: Fontenelle, C.Q., Wang, Z., Fossey, C., Cailly, T., Linclau, B., Fabis, F., Design of fluorinated 5-HT4R antagonists: influence of the basicity and lipophilicity toward the 5-HT4R binding affinities, Bioorganic & Medicinal Chemistry (2013), doi: http://dx.doi.org/10.1016/j.bmc.2013.08.061 This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form.



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